
ヨシダ ユウタ吉田 悠太講師Yuta Yoshida
■研究者基本情報
学歴
経歴
委員歴
■研究活動情報
受賞
- 2023年09月, アグリテックグランプリ2023 ニップン賞, 株式会社リバネス
- 2022年08月, 第9回 日本時間栄養学会学術大会 優秀発表賞
- 2020年03月, 2020年度 日本畜産学会奨励賞, 日本畜産学会
- 2020年03月, 2019年度 生物資源環境科学府賞, 九州大学大学院
- 2019年03月, 優秀発表賞 (第125回大会), 日本畜産学会
- 2019年03月, English Presentation Award (第125回大会), 日本畜産学会
- 2017年09月, 優秀発表賞 (第123回大会), 日本畜産学会
- 2017年09月, English Presentation Award (第123回大会), 日本畜産学会
論文
- Potential non-invasive biomarkers of chronic sleep disorders identified by salivary metabolomic profiling among middle-aged Japanese men
Katsutaka Oishi; Yuta Yoshida; Kosuke Kaida; Kozue Terai; Hiroyuki Yamamoto; Atsushi Toyoda, Springer Science and Business Media LLC
Scientific Reports, 2025年04月21日, [査読有り] - Effective cultivation conditions and safety evaluation of filamentous cyanobacteria producing phycocyanins with antiglycation activities
Jinichi Aoki; Takato Ozaki; Runa Koshikawa; Daisaku Sasaki; Katsuyoshi Kitajima; Yuta Yoshida; Hiromi Nakajima; Munehiko Asayama, Elsevier BV
Journal of Biotechnology, 2024年08月, [査読有り] - Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment
Hideo Hagihara; Hirotaka Shoji; Satoko Hattori; Giovanni Sala; Yoshihiro Takamiya; Mika Tanaka; Masafumi Ihara; Mihiro Shibutani; Izuho Hatada; Kei Hori; Mikio Hoshino; Akito Nakao; Yasuo Mori; Shigeo Okabe; Masayuki Matsushita; Anja Urbach; Yuta Katayama; Akinobu Matsumoto; Keiichi I Nakayama; Shota Katori; Takuya Sato; Takuji Iwasato; Haruko Nakamura; Yoshio Goshima; Matthieu Raveau; Tetsuya Tatsukawa; Kazuhiro Yamakawa; Noriko Takahashi; Haruo Kasai; Johji Inazawa; Ikuo Nobuhisa; Tetsushi Kagawa; Tetsuya Taga; Mohamed Darwish; Hirofumi Nishizono; Keizo Takao; Kiran Sapkota; Kazutoshi Nakazawa; Tsuyoshi Takagi; Haruki Fujisawa; Yoshihisa Sugimura; Kyosuke Yamanishi; Lakshmi Rajagopal; Nanette Deneen Hannah; Herbert Y Meltzer; Tohru Yamamoto; Shuji Wakatsuki; Toshiyuki Araki; Katsuhiko Tabuchi; Tadahiro Numakawa; Hiroshi Kunugi; Freesia L Huang; Atsuko Hayata-Takano; Hitoshi Hashimoto; Kota Tamada; Toru Takumi; Takaoki Kasahara; Tadafumi Kato; Isabella A Graef; Gerald R Crabtree; Nozomi Asaoka; Hikari Hatakama; Shuji Kaneko; Takao Kohno; Mitsuharu Hattori; Yoshio Hoshiba; Ryuhei Miyake; Kisho Obi-Nagata; Akiko Hayashi-Takagi; Léa J Becker; Ipek Yalcin; Yoko Hagino; Hiroko Kotajima-Murakami; Yuki Moriya; Kazutaka Ikeda; Hyopil Kim; Bong-Kiun Kaang; Hikari Otabi; Yuta Yoshida; Atsushi Toyoda; Noboru H Komiyama; Seth GN Grant; Michiru Ida-Eto; Masaaki Narita; Ken-ichi Matsumoto; Emiko Okuda-Ashitaka; Iori Ohmori; Tadayuki Shimada; Kanato Yamagata; Hiroshi Ageta; Kunihiro Tsuchida; Kaoru Inokuchi; Takayuki Sassa; Akio Kihara; Motoaki Fukasawa; Nobuteru Usuda; Tayo Katano; Teruyuki Tanaka; Yoshihiro Yoshihara; Michihiro Igarashi; Takashi Hayashi; Kaori Ishikawa; Satoshi Yamamoto; Naoya Nishimura; Kazuto Nakada; Shinji Hirotsune; Kiyoshi Egawa; Kazuma Higashisaka; Yasuo Tsutsumi; Shoko Nishihara; Noriyuki Sugo; Takeshi Yagi; Naoto Ueno; Tomomi Yamamoto; Yoshihiro Kubo; Rie Ohashi; Nobuyuki Shiina; Kimiko Shimizu; Sayaka Higo-Yamamoto; Katsutaka Oishi; Hisashi Mori; Tamio Furuse; Masaru Tamura; Hisashi Shirakawa; Daiki X Sato; Yukiko U Inoue; Takayoshi Inoue; Yuriko Komine; Tetsuo Yamamori; Kenji Sakimura; Tsuyoshi Miyakawa, Increased levels of lactate, an end-product of glycolysis, have been proposed as a potential surrogate marker for metabolic changes during neuronal excitation. These changes in lactate levels can result in decreased brain pH, which has been implicated in patients with various neuropsychiatric disorders. We previously demonstrated that such alterations are commonly observed in five mouse models of schizophrenia, bipolar disorder, and autism, suggesting a shared endophenotype among these disorders rather than mere artifacts due to medications or agonal state. However, there is still limited research on this phenomenon in animal models, leaving its generality across other disease animal models uncertain. Moreover, the association between changes in brain lactate levels and specific behavioral abnormalities remains unclear. To address these gaps, the International Brain pH Project Consortium investigated brain pH and lactate levels in 109 strains/conditions of 2294 animals with genetic and other experimental manipulations relevant to neuropsychiatric disorders. Systematic analysis revealed that decreased brain pH and increased lactate levels were common features observed in multiple models of depression, epilepsy, Alzheimer’s disease, and some additional schizophrenia models. While certain autism models also exhibited decreased pH and increased lactate levels, others showed the opposite pattern, potentially reflecting subpopulations within the autism spectrum. Furthermore, utilizing large-scale behavioral test battery, a multivariate cross-validated prediction analysis demonstrated that poor working memory performance was predominantly associated with increased brain lactate levels. Importantly, this association was confirmed in an independent cohort of animal models. Collectively, these findings suggest that altered brain pH and lactate levels, which could be attributed to dysregulated excitation/inhibition balance, may serve as transdiagnostic endophenotypes of debilitating neuropsychiatric disorders characterized by cognitive impairment, irrespective of their beneficial or detrimental nature., eLife Sciences Publications, Ltd
eLife, 2024年03月26日, [査読有り] - Characterization of taste sensitivities to amino acids and sugars by conditioned taste aversion learning in chickens
Yuta Yoshida; Shu Fujishiro; Ryota Kawai; Fuminori Kawabata, 筆頭著者, Elsevier BV
animal, 2024年02月, [査読有り] - Metabolic profiles of saliva in male mouse models of chronic sleep disorders induced by psychophysiological stress.
Katsutaka Oishi; Yuhei Yajima; Yuta Yoshida; Hideo Hagihara; Tsuyoshi Miyakawa; Sayaka Higo-Yamamoto; Atsushi Toyoda, Disordered sleep is a global social problem and an established significant risk factor for psychological and metabolic diseases. We profiled non-targeted metabolites in saliva from mouse models of chronic sleep disorder (CSD). We identified 288 and 55 metabolites using CE-FTMS and LC-TOFMS, respectively, among which concentrations of 58 (CE-FTMS) and three (LC-TOFMS) were significantly changed by CSD. Pathway analysis revealed that CSD significantly suppressed glycine, serine and threonine metabolism. Arginine and proline metabolic pathways were among those that were both upregulated and downregulated. Pathways of alanine, aspartate and glutamate metabolism, genetic information processing, and the TCA cycle tended to be downregulated, whereas histidine metabolism tended to be upregulated in mice with CSD. Pyruvate, lactate, malate, succinate and the glycemic amino acids alanine, glycine, methionine, proline, and threonine were significantly decreased, whereas 3-hydroxybutyric and 2-hydroxybutyric acids associated with ketosis were significantly increased, suggesting abnormal glucose metabolism in mice with CSD. Increases in the metabolites histamine and kynurenic acid that are associated with the central nervous system- and decreased glycine, might be associated with sleep dysregulation and impaired cognitive dysfunction in mice with CSD. Our findings suggested that profiling salivary metabolites could be a useful strategy for diagnosing CSD.
Scientific reports, 2023年07月10日, [査読有り] - Impacts of Subchronic and Mild Social Defeat Stress on Plasma Putrefactive Metabolites and Cardiovascular Structure in Male Mice
Atsushi Toyoda; Kina Kawakami; Yuto Amano; Hideaki Nishizawa; Shin-ichi Nakamura; Takahiro Kawase; Yuta Yoshida; Hodaka Suzuki; Takamitsu Tsukahara, Psychosocial stress precipitates mental illnesses, such as depression, and increases the risk of other health problems, including cardiovascular diseases. In this study, we observed the effects of psychosocial stress on the histopathological features of systemic organs and tissues in a mouse psychosocial stress model, namely the subchronic and mild social defeat stress (sCSDS) model. There were several pathological findings in the tissues of both sCSDS and control mice. Mild fibrosis of the heart was observed in sCSDS mice but not in control mice. Extramedullary hematopoiesis in the spleen and hemorrhage in the lungs were observed in both the control and sCSDS mice. Focal necrosis of the liver was seen only in control mice. Furthermore, putrefactive substances in the blood plasma were analyzed because these metabolites originating from intestinal fermentation might be linked to heart fibrosis. Among them, plasma p-cresyl glucuronide and p-cresyl sulfate concentrations significantly increased owing to subchronic social defeat stress, which might influence cardiac fibrosis in sCSDS mice. In conclusion, several pathological features such as increased cardiac fibrosis and elevated plasma putrefactive substances were found in sCSDS mice. Thus, sCSDS mice are a potential model for elucidating the pathophysiology of psychosocial stress and heart failure., MDPI AG
International Journal of Molecular Sciences, 2023年01月08日, [査読有り] - Identification of salivary microRNA profiles in male mouse model of chronic sleep disorder
Yuta Yoshida; Yuhei Yajima; Yuri Fujikura; Haotong Zhuang; Sayaka Higo-Yamamoto; Atsushi Toyoda; Katsutaka Oishi, 筆頭著者, Chronic sleep disorders (CSD) comprise a potential risk factor for metabolic and cardiovascular diseases, obesity and stroke. Thus, the identification of biomarkers for CSD is an important step in the early prevention of metabolic dysfunctions induced by sleep dysfunction. Diagnostic saliva samples can be easily and noninvasively collected. Thus, we aimed to identify whole microRNA (miRNA) profiles of saliva in control and psychophysiologically stressed CSD mouse models and compare them at Zeitgeber time (ZT) 0 (lights on) and ZT12 (lights off). The findings of two-way ANOVA revealed that the expression of 342 and 109 salivary miRNAs was affected by CSD and the time of day, respectively. Interactions were found in 122 miRNAs among which, we identified 197 (ZT0) and 62 (ZT12) upregulated, and 40 (ZT0) and seven (ZT12) downregulated miRNAs in CSD mice. We showed that miR-30c-5p, which is elevated in the plasma of patients with hypersomnia, was upregulated in the saliva of CSD mice collected at ZT0. The miRNAs, miR-10a-5p, miR-146b-5p, miR-150-5p, and miR-25-3p are upregulated in the serum of humans with poor sleep quality, and these were also upregulated in the saliva of CSD mice collected at ZT0. The miRNAs miR-30c, miR146b-5p, miR150, and miR-25-5p are associated with cardiovascular diseases, and we found that plasma concentrations of brain natriuretic peptides were significantly increased in CSD mice. The present findings showed that salivary miRNA profiles could serve as useful biomarkers for predicting CSD., Informa UK Limited
Stress, 2023年01月02日, [査読有り] - Salivary microRNA and Metabolic Profiles in a Mouse Model of Subchronic and Mild Social Defeat Stress
Yuta Yoshida; Yuhei Yajima; Kina Kawakami; Shin-ichi Nakamura; Takamitsu Tsukahara; Katsutaka Oishi; Atsushi Toyoda, 筆頭著者, Identification of early biomarkers of stress is important for preventing mood and anxiety disorders. Saliva is an easy-to-collect and non-invasive diagnostic target. The aim of this study was to characterize the changes in salivary whole microRNAs (miRNAs) and metabolites in mice subjected to subchronic and mild social defeat stress (sCSDS). In this study, we identified seven upregulated and one downregulated miRNAs/PIWI-interacting RNA (piRNA) in the saliva of sCSDS mice. One of them, miR-208b-3p, which is reported as a reliable marker for myocardial infarction, was upregulated in the saliva of sCSDS mice. Histological analysis showed frequent myocardial interstitial fibrosis in the heart of such mice. In addition, gene ontology and pathway analyses suggested that the pathways related to energy metabolism, such as the oxidative phosphorylation and the pentose phosphate pathway, were significantly related to the miRNAs affected by sCSDS in saliva. In contrast, salivary metabolites were not significantly changed in the sCSDS mice, which is consistent with our previous metabolomic study on the plasma of sCSDS mice. Taken in the light of previous studies, the present study provides novel potential stress biomarkers for future diagnosis using saliva., MDPI AG
International Journal of Molecular Sciences, 2022年11月21日, [査読有り] - Oral expressions and functional analyses of the extracellular calcium-sensing receptor (CaSR) in chicken
Hikaru Omori; Yuko Kawabata; Yuta Yoshida; Yutaro Nagamoto; Fuminori Kawabata; Shotaro Nishimura; Shoji Tabata, Abstract
In vertebrates, the extracellular calcium-sensing receptor (CaSR) plays a key role in calcium homeostasis by sensing slight changes in extracellular Ca2+. CaSR is also expressed in mammals including rodent taste cells and is involved in sensing kokumi, a rich, savory quality that enhances the intensities of salty, sweet, and umami tastes. In this study, we focused on chicken CaSR (cCaSR) since calcium is an essential nutrient that is necessary for making eggshell and for the extremely rapid initial growth of bones. First we confirmed that cCaSR is expressed in taste cells. Next we cloned the cCaSR gene from kidney and transiently transfected human embryonic kidney 293 T (HEK293T) cells with the recombinant cCaSR, or empty vector and looked for the agonists and allosteric modulators (including kokumi substances) of cCaSR by Ca2+ imaging. We found that cCaSR was activated by extracellular Ca2+ and Mg2+ in a dose dependent manner. Several L-amino acids and kokumi substances such as glutathione enhanced the response of cCaSR. In addition, NPS2143 as a negative allosteric modulator of human CaSR negatively modulated the response of cCaSR. These results suggest that cCaSR can sense extracellular Ca2+ and Mg2+ as well as positive and negative allosteric modulators. Taken together, the results imply that CaSR might be a multifunctional receptor for calcium, amino acids, and kokumi substances in chicken. The present finding that functional CaSR is expressed in the chicken oral tissues will allow us to further elucidate the physiological role of CaSR in the chickens' taste sense, and to create new feeds that will contribute to the poultry industry., Springer Science and Business Media LLC
Scientific Reports, 2022年10月22日, [査読有り] - Periostin Contributes to Fibrocartilage Layer Growth of the Patella Tendon Tibial Insertion in Mice
Hirotaka Mutsuzaki; Yuta Yoshida; Hiromi Nakajima, Background and Objectives: The influence of periostin on the growth of the patella tendon (PT) tibial insertion is unknown. The research described here aimed to reveal the contribution of periostin to the growth of fibrocartilage layers of the PT tibial insertion using periostin knockout mice. Materials and Methods: In both the wild-type (WD; C57BL/6N, periostin +/+; n = 54) and periostin knockout (KO; periostin −/−; n = 54) groups, six mice were euthanized on day 1 and at 1, 2, 3, 4, 6, 8, 10, and 12 weeks of age. Chondrocyte proliferation and apoptosis, number of chondrocytes, safranin O-stained glycosaminoglycan (GAG) area, staining area of type II collagen, and length of the tidemark were investigated. Results: Chondrocyte proliferation and apoptosis in KO were lower than those in WD on day 1 and at 1, 4, and 8 weeks and on day 1 and at 4, 6, and 12 weeks, respectively. Although the number of chondrocytes in both groups gradually decreased, it was lower in KO than in WD on day 1 and at 8 and 12 weeks. In the extracellular matrix, the GAG-stained area in KO was smaller than that in WD on day 1 and at 1, 4, 8, 10, and 12 weeks. The staining area of type II collagen in KO was smaller than that in WD at 8 weeks. The length of the tidemark in KO was shorter than that in WD at 4 and 6 weeks. Conclusion: Loss of periostin led to decreased chondrocyte proliferation, chondrocyte apoptosis, and the number of chondrocytes in the growth process of the PT tibial insertion. Moreover, periostin decreased and delayed GAG and type II collagen production and delayed tidemark formation in the growth process of the PT tibial insertion. Periostin can, therefore, contribute to the growth of fibrocartilage layers in the PT tibial insertion. Periostin deficiency may result in incomplete growth of the PT tibial insertion., MDPI AG
Medicina, 2022年07月19日, [査読有り] - Behavioral responses to sweet compounds via T1R2-independent pathways in chickens
Momoko Higashida; Yuta Yoshida; Yuko Kawabata; Yuki Matsui; Shotaro Nishimura; Shoji Tabata; Fuminori Kawabata, Elsevier BV
Poultry Science, 2022年07月, [査読有り] - Conditioned Taste Aversion to L-Amino Acid Taste Stimuli and Oral Transcriptional Changes to Type 1 Taste Receptors T1R1 and T1R3 on Chronic Exposure to L-Alanine Solution in Chickens
Yuta Yoshida; Ryota Tanaka; Shu Fujishiro; Shotaro Nishimura; Shoji Tabata; Fuminori Kawabata, 筆頭著者, Japan Poultry Science Association
The Journal of Poultry Science, 2022年04月, [査読有り] - Chicken taste receptors and perception: recent advances in our understanding of poultry nutrient-sensing systems
Yuta Yoshida; Shotaro Nishimura; Shoji Tabata; Fuminori Kawabata, 筆頭著者, Informa UK Limited
World's Poultry Science Journal, 2022年01月02日, [査読有り] - Identification of Ligands for Chicken Transient Receptor Potential Ankyrin 1 Channel and Chemosensory Perception of Herbal Compounds in Chickens
Fuminori Kawabata; Kana Murayama; Yuta Yoshida; Ruojun Liang; Shotaro Nishimura; Shoji Tabata, Japan Poultry Science Association
The Journal of Poultry Science, 2022年01月, [査読有り] - Fatty Acid Taste Receptor GPR120 Activation by Arachidonic Acid, Eicosapentaenoic Acid, and Docosahexaenoic Acid in Chickens
Fuminori Kawabata; Yuta Yoshida; Seiga Kuba; Yuko Kawabata; Shotaro Nishimura; Shoji Tabata, Japan Poultry Science Association
The Journal of Poultry Science, 2021年11月, [査読有り] - Subchronic and mild social defeat stress downregulates peripheral expression of sweet and umami taste receptors in male mice
Yuta Yoshida; Misa Miyazaki; Yuhei Yajima; Atsushi Toyoda, 筆頭著者, Elsevier BV
Biochemical and Biophysical Research Communications, 2021年11月, [査読有り] - Overlapping distributions of mammalian types I, II, and III taste cell markers in chicken taste buds
Yuta Yoshida; Fuminori Kawabata; Shotaro Nishimura; Shoji Tabata, 筆頭著者, Elsevier BV
Biochemical and Biophysical Research Communications, 2021年09月, [査読有り] - The umami receptor T1R1–T1R3 heterodimer is rarely formed in chickens
Yuta Yoshida; Fuminori Kawabata; Shotaro Nishimura; Shoji Tabata, 筆頭著者, Abstract
The characterization of molecular mechanisms underlying the taste-sensing system of chickens will add to our understanding of their feeding behaviors in poultry farming. In the mammalian taste system, the heterodimer of taste receptor type 1 members 1/3 (T1R1/T1R3) functions as an umami (amino acid) taste receptor. Here, we analyzed the expression patterns of T1R1 and T1R3 in the taste cells of chickens, labeled by the molecular markers for chicken taste buds (vimentin and α-gustducin). We observed that α-gustducin was expressed in some of the chicken T1R3-positive taste bud cells but rarely expressed in the T1R1-positive and T2R7-positive taste bud cells. These results raise the possibility that there is another second messenger signaling system in chicken taste sensory cells. We also observed that T1R3 and α-gustducin were expressed mostly in the vimentin-positive taste bud cells, whereas T1R1 and bitter taste receptor (i.e., taste receptor type 2 member 7, T2R7) were expressed largely in the vimentin-negative taste bud cells in chickens. In addition, we observed that T1R1 and T1R3 were co-expressed in about 5% of chickens' taste bud cells, which express T1R1 or T1R3. These results suggest that the heterodimer of T1R1 and T1R3 is rarely formed in chickens’ taste bud cells, and they provide comparative insights into the expressional regulation of taste receptors in the taste bud cells of vertebrates., Springer Science and Business Media LLC
Scientific Reports, 2021年06月10日, [査読有り] - Evolvement of taste sensitivity and taste buds in chickens during selective breeding
Yuta Yoshida; Fuminori Kawabata; Shoji Tabata; Samuel E. Aggrey; Romdhane Rekaya; Hong-Xiang Liu, 筆頭著者, Elsevier BV
Poultry Science, 2021年06月, [査読有り] - Taste buds are not derived from neural crest in mouse, chicken, and zebrafish
Wenxin Yu; Zhonghou Wang; Brett Marshall; Yuta Yoshida; Renita Patel; Xiaogang Cui; Rebecca Ball; Linlin Yin; Fuminori Kawabata; Shoji Tabata; Wenbiao Chen; Robert N. Kelsh; James D. Lauderdale; Hong-Xiang Liu, Elsevier BV
Developmental Biology, 2021年03月, [査読有り] - ニワトリの味覚受容:うま味に対する行動応答とうま味受容体の発現
吉田 悠太; 川端 二功; 西村 正太郎; 田畑 正志, 筆頭著者, Japanese Society of Animal Science
日本畜産学会報, 2021年02月, [査読有り], [招待有り] - Research Note: Behavioral preference and conditioned taste aversion to oleic acid solution in chickens
Fuminori Kawabata; Yuta Yoshida; Yuki Inoue; Yuko Kawabata; Shotaro Nishimura; Shoji Tabata, Elsevier BV
Poultry Science, 2021年01月, [査読有り] - Bitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in Chickens
Fuminori Kawabata; Bapon Dey; Yuta Yoshida; Shotaro Nishimura; Shoji Tabata, Japan Poultry Science Association
The Journal of Poultry Science, 2020年, [査読有り] - Abundant proliferating cells within early chicken taste buds indicate a potentially "built-in" progenitor system for taste bud growth during maturation in hatchlings.
Wang Z; Yoshida Y; Kramer NE; Kawabata F; Tabata S; Kim WK; Liu HX
Histology and histopathology, 2019年05月, [査読有り] - Bitter taste receptor T2R7 and umami taste receptor subunit T1R1 are expressed highly in Vimentin-negative taste bud cells in chickens
Yuta Yoshida; Zhonghou Wang; Kayvan F. Tehrani; Emily G. Pendleton; Ryota Tanaka; Luke J. Mortensen; Shotaro Nishimura; Shoji Tabata; Hong-Xiang Liu; Fuminori Kawabata, 筆頭著者, Elsevier BV
Biochemical and Biophysical Research Communications, 2019年04月, [査読有り] - Short-term perception of and conditioned taste aversion to umami taste, and oral expression patterns of umami taste receptors in chickens
Yuta Yoshida; Fuminori Kawabata; Yuko Kawabata; Shotaro Nishimura; Shoji Tabata, 筆頭著者, Elsevier BV
Physiology & Behavior, 2018年07月, [査読有り] - Expression levels of taste-related genes in palate and tongue tip, and involvement of transient receptor potential subfamily M member 5 (TRPM5) in taste sense in chickens
Yuta Yoshida; Fuminori Kawabata; Yuko Kawabata; Shotaro Nishimura; Shoji Tabata, 筆頭著者, Wiley
Animal Science Journal, 2018年02月, [査読有り] - Identification of functional bitter taste receptors and their antagonist in chickens
Bapon Dey; Fuminori Kawabata; Yuko Kawabata; Yuta Yoshida; Shotaro Nishimura; Shoji Tabata, Elsevier BV
Biochemical and Biophysical Research Communications, 2017年01月, [査読有り] - Expressions of multiple umami taste receptors in oral and gastrointestinal tissues, and umami taste synergism in chickens
Yuta Yoshida; Yuko Kawabata; Fuminori Kawabata; Shotaro Nishimura; Shoji Tabata, 筆頭著者, Elsevier BV
Biochemical and Biophysical Research Communications, 2015年10月, [査読有り] - 家禽の味覚受容体に関する研究
川端二功; 川端由子; 廣瀬のぞみ; 澤村亮; 吉田悠太; 西村正太郎; 田畑正志
栄養生理研究会報, 2015年04月, [査読有り], [招待有り]
MISC
- 第27回若手企画シンポジウム 「『データの洪水』を乗り越えるすべ〜オミクス解析の観点から〜」の開催報告
小川 伸一郎; 吉田 悠太; 渡邊 源哉
Nihon Chikusan Gakkaiho, 2025年02月25日 - 第1回オンラインサイエンスキャンプ「若手が切り拓くアニマルサイエンスの最前線」の開催報告
悠太 吉田; 伸一郎 小川; 利衣 澤戸; 裕美 池田; 源哉 渡邊
Nihon Chikusan Gakkaiho, 2024年11月25日
筆頭著者 - 第26回若手企画シンポジウム「どうする?どうなる!?日本の畜産業界 〜現状と現場を知る〜」の開催報告
大塚 剛司; 長澤 麻央; 鈴木 貴弘; 吉田 悠太; 渡邊 源哉
Nihon Chikusan Gakkaiho, 2024年05月25日 - 〔主要な業績〕第4回日本畜産学会若手企画サイエンスキャンプ ~若手が切り拓くアニマルサイエンスの最前線~の開催報告
吉田 悠太; 島元 紗希; 牧野 良輔; 新居 隆浩
Nihon Chikusan Gakkaiho, 2023年08月25日
筆頭著者 - Expression of Umami Taste Receptors and Behavioral Reactions to Umami Taste in Chickens
Yoshida Yuta; Kawabata Fuminori; Kawabata Yuko; Nishimura Shotaro; Tabata Shoji
CHEMICAL SENSES, 2018年05月, [査読有り]
筆頭著者
講演・口頭発表等
- ⼼理社会的なストレスが味蕾に及ぼす影響の検討
宮崎 美沙; 豊田 淳; 吉田 悠太
第46回 日本分子生物学会年会, 2023年12月07日 - ⼼理社会的なストレスが塩味嗜好性に及ぼす影響の検討
門脇 崇; 湯澤 亜利沙; 豊田 淳; 吉田 悠太
第46回 日本分子生物学会年会, 2023年12月07日 - A study on the relationship between salivary miR-208b-3p and stress-induced cardiac fibrosis in male mice subjected to sub-chronic and mild social defeat stress (sCSDS)
Finandya Fatihasari Yuta; Yoshida Yuhei; Yajima Kina; Kawakami; Shin-ichi Nakamura; Takamitsu Tsukahara; Katsutaka Oishi; Atsushi Toyoda
第46回 日本分子生物学会年会, 2023年12月06日 - 〔主要な業績〕ニワトリが味覚を感じるアミノ酸と糖のプロファイリング
吉田悠太; 藤代柊; 河合亮汰; 川端二功
日本家禽学会 2023年度秋季大会, 2023年09月21日 - 〔主要な業績〕食性の異なる動物における新規味覚受容体候補遺伝子の発現
吉田悠太; 宮口右二; 宮﨑照雄; 冨田和秀; 佐々木誠一
日本畜産学会 第131回大会, 2023年09月20日 - 〔主要な業績〕食性の異なる動物における長鎖脂肪酸受容体の応答性の比較
藤代柊; 久保田未優; 川端二功; 吉田悠太
日本畜産学会 第131回大会, 2023年09月19日 - 慢性的な睡眠障害モデルマウスの唾液におけるmiRNA-seq解析
吉田悠太; 谷島優平; 藤倉祐里; 庄皓桐; 山本明花; 豊田淳; 大石勝隆
第29回 日本時間生物学会学術大会, 2022年12月03日 - ニワトリが味覚を感じるL-アミノ酸のプロファイリング
藤代柊; 川端二功; 吉田悠太
日本畜産学会 第130回大会, 2022年09月16日
20220914, 20220917 - 慢性的な睡眠障害モデルマウスにおける唾液microRNAプロファイルの解析
吉田悠太; 谷島優平; 藤倉祐里; 庄皓桐; 山本明花; 豊田淳; 大石勝隆
第9回 日本時間栄養学会学術大会, 2022年08月26日 - 塩味の嗜好性を制御する脳神経基盤の解明
吉田悠太
ソルトサイエンス研究財団 第34回助成研究発表会, 2022年07月26日 - 動物の食性と味覚の研究
吉田悠太
第24回日本畜産学会若手企画シンポジウム, 2022年03月30日, [招待有り] - Systematic analysis of brain lactate and pH levels in 73 animal models related to neuropsychiatric conditions
Hideo Hagihara; Hirotaka Shoji; International Brain pH Project Consortium; Tsuyoshi Miyakawa
ACNP Annual Meeting 2021
20211205, 20211208 - 畜産動物の味覚研究について
吉田悠太
第63回茨城県畜産研究会シンポジウム, 2021年03月, [招待有り] - 動物の味覚研究の将来展望
吉田悠太
第21回日本畜産学会若手企画シンポジウム, 2020年11月13日, [招待有り] - ニワトリ脂肪酸受容体GPR120の新規アゴニストの同定
川端二功; 久場星河; 吉田悠太; 川端由子; 西村正太郎; 田畑正志
第13回日本暖地畜産学会 沖縄大会, 2020年10月25日 - Expression of umami taste receptors in the taste bud cells of chickens, and behavioral responses to umami taste in chickens
Yoshida Y; Wang Z; Tehrani KF; Pendleton EG; Mortensen LJ; Nishimura S; Tabata S; Liu HX; Kawabata F
The 18th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception, 2019年11月02日 - Taste receptors and taste behaviors in chickens
Kawabata F; Kawabata Y; Yoshida Y; Omori H; Higashida M; Dey B; Liang R; Murayama K; Hayase Y; Araki M; Nishimura S; Liu HX; Tabata S
THE 48th NAITO CONFERENCE on Integrated Sensory Sciences-Pain, Itch, Smell and Taste, 2019年10月10日 - Bitter Taste Receptor T2R7 and Umami Taste Receptor Subunit T1R1 are Expressed Largely in Vimentin-Negative Taste Bud Cells of Chickens
Yoshida Y; Wang Z; Tehrani KF; Pendleton EG; Tanaka R; Mortensen LJ; Nishimura S; Tabata S; Liu HX; Kawabata F
The Association for Chemoreception Sciences 41th annual meeting, 2019年04月15日 - Bitter Taste Receptor T2R7 and Umami Taste Receptor Subunit T1R1 are Expressed in the Taste Bud Cells of Chickens
吉田悠太; Wang Z; Tehrani KF; Pendleton EG; 田中崚太; Mortensen LJ; 西村正太郎; 田畑正志; Liu HX; 川端二功
日本畜産学会 第125回大会, 2019年03月28日 - Analysis of mRNA expressions and functions of sour taste receptor candidate PKD2L1 in chickens
Araki M; Kawabata F; Kawabata Y; Yoshida Y; Nishimura S; Tabata S
The 17th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception, 2018年12月01日 - Taste systems in chickens
Kawabata F; Kawabata F; Yoshida Y; Dey B; Hirose N; Sawamura R; Omori H; Higashida M; Nishimura S; Tabata S
English Poster Session “Meet the Professor”, 121th Annual meeting of Japan Poultry Science Association, 2018年09月06日 - Umami taste sense in chickens characterized by the receptor expression and behavioral responses
吉田悠太; 川端二功; 川端由子; 西村正太郎; 田畑正志
日本畜産学会 第123回大会, 2017年09月06日 - Expression of Umami Taste Receptors and Behavioral Reactions to Umami Taste in Chickens
Yoshida Y; Kawabata F; Kawabata Y; Nishimura S; Tabata S
The Association for Chemoreception Sciences 39th annual meeting, 2017年04月27日 - Expression patterns of multiple umami taste receptors in chickens; metabotropic glutamate receptor type 4 is not involved in umami receptor systems of chickens
Yoshida Y; Kawabata F; Nishimura S; Tabata S
The 15th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception, 2016年12月04日 - Expression patterns of taste sensors in oral and gastrointestinal tissues of chickens
Kawabata F; Kawabata Y; Yoshida Y; Higashida M; Ohmori H; Nishimura S; Tabata S
The 17th AAAP Animal Science Congress, 2016年08月25日 - ニワトリにおけるうま味の相乗効果とうま味受容体遺伝子発現解析
吉田悠太; 川端二功; 川端由子; 西村正太郎; 田畑正志
日本畜産学会 第121回大会, 2016年03月28日 - The receptors for fat, bitter, and umami tastes in chickens
Kawabata F; Yoshida Y; Kawabata Y; Nishimura S; Tabata S
The 13th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception, 2015年11月04日 - ニワトリにおけるうま味の相乗効果とうま味受容体群の発現解析
吉田悠太; 川端二功; 川端由子; 西村正太郎; 田畑正志
日本味と匂学会 第49回大会, 2015年09月26日 - ニワトリのうま味に対する嗜好性およびうま味受容体遺伝子の発現解析
吉田悠太; 川端二功; 川端由子; 西村正太郎; 田畑正志
日本畜産学会 第119回大会, 2015年03月29日
担当経験のある科目(授業)
- 専攻研究
2024年04月 - 現在 - 特別演習
2024年04月 - 現在 - プレゼンテーション演習
2024年04月 - 現在 - 動物生体機構学特論
2024年04月 - 現在 - Advanced Animal Physiology
2024年04月 - 現在 - 技術と社会
2024年04月 - 現在 - 動物科学演習
2024年04月 - 現在 - 〔主要な業績〕動物生理学
2021年 - 現在 - 〔主要な業績〕動物解剖学・生化学実験
2021年 - 現在 - 動物科学総論
2021年 - 現在 - 農学入門
2021年 - 現在 - 食生命科学入門
2021年 - 現在 - 食生命科学演習
2021年 - 現在 - ゼミナール【食生命科学科】
2021年 - 現在 - 卒業論文【食生命科学科】
2021年 - 現在 - 情報リテラシー【前期】
2025年04月 - 2026年03月 - 大学入門ゼミ【前期】フレッシュマンゼミナール
2025年04月 - 2026年03月 - 科学と倫理A
2024年04月 - 2025年03月 - 大学入門ゼミ【前期】フレッシュマンゼミナール
2021年04月 - 2022年03月
共同研究・競争的資金等の研究課題
- 精神ストレスを介した塩味嗜好性の新規制御メカニズムの解明
公益財団法人ロッテ財団 奨励研究助成 (A)
2023年04月 - 2026年03月 - ウズラの苦味受容特性の理解と飼養への応用
2024年度 旗影会研究助成
2024年04月 - 2025年03月 - 畜産動物の脂肪酸味覚受容体の機能解析 (II)
公益財団法人伊藤記念財団 令和5年度研究助成
2023年04月 - 2024年03月 - 畜産動物の脂肪酸味覚受容体の機能解析
公益財団法人伊藤記念財団 令和4年度研究助成
2022年04月 - 2023年03月 - 塩味嗜好性を制御する脳神経回路の解明
2022年度 笹川科学研究助成
2022年04月 - 2023年03月 - 畜産動物の有郭乳頭からの味蕾オルガノイド培養系の構築
2022年度 旗影会研究助成
2022年04月 - 2023年03月 - 塩味の嗜好性を制御する脳神経基盤の解明
公益財団法人ソルト・サイエンス研究財団 研究助成
2021年04月 - 2022年03月 - ブタの味蕾における味覚受容体レパートリーの解明
2021年度 旗影会研究助成
2021年04月 - 2022年03月 - ニワトリの味蕾における味覚シグナル伝達機構の解明
2020年04月 - 2021年03月 - ニワトリのうま味受容機構の解明:畜産学と比較生理学への貢献
若手研究者海外挑戦プログラム
2018年03月 - 2019年01月 - ニワトリにおけるうま味の相乗効果とうま味受容体機能の解明
平成28年度 笹川科学研究助成
2016年04月 - 2017年03月
社会貢献活動
- 〔主要な業績〕第2回 日本畜産学会若手企画オンラインサイエンスキャンプ 〜Animal Science Dialogue〜
講師
日本畜産学会若手企画委員会, 2025年03月11日 - 〔主要な業績〕Introduction of the College of Agriculture, Ibaraki University, and our collaboration with Indonesian universities. General Lecture and Collaboration Initiation: Ibaraki University and Sultan Ageng Tirtayasa University Strengthening Academic Partnership
講師
Sultan Ageng Tirtayasa University, 2025年03月08日 - 〔主要な業績〕味覚の科学
講師
茨城県立竹園高等学校, 模擬授業, 2024年11月07日 - 血液の細胞を観察してみよう!
講師
茨城大学農学部ミニオープンキャンパス, 2024年10月19日 - 〔主要な業績〕「味覚の科学/血液の細胞を観察しよう!」
講師
高校生公開講座, 2024年08月02日 - 〔主要な業績〕味覚の科学
講師
水戸葵陵高等学校, 模擬授業, 2024年07月04日 - A taste biosensor for livestock and companion animals
講師
Dickinson State University, 2024年05月15日 - 〔主要な業績〕第1回 日本畜産学会若手企画オンラインサイエンスキャンプ
講師
2024年03月21日 - 動物の味覚バイオセンサー
出演
株式会社リバネス, アグリテックグランプリ2023, 2023年09月16日 - 味覚の科学
講師
茨城大学オープンキャンパス2023 模擬授業, 2023年07月22日 - 〔主要な業績〕味覚の科学
講師
茨城県立竜ヶ崎第一高等学校 模擬授業, 2023年07月10日 - 〔主要な業績〕第4回 (公社) 日本畜産学会若手企画サイエンスキャンプ 茨城大学阿見キャンパス
講師
2023年02月11日 - 2023年02月12日 - 動物の味覚研究
講師
茨城大学・日立市かみね動物園共同勉強会, 2022年12月21日 - 〔主要な業績〕味覚の科学
講師
茨城県立下妻第一高等学校 模擬授業, 2022年11月11日 - 動物の味覚バイオセンサーの研究
出演
アグリビジネス創出フェア2022 東京ビッグサイト, 2022年10月26日 - 2022年10月28日 - 〔主要な業績〕味覚の科学
講師
茨城県立土浦第二高等学校 模擬授業, 2022年10月26日 - 〔主要な業績〕味覚研究を通じた農医連携をめざして
講師
第14回 三大学交流セミナー 〜阿見町発、新しい医療・農連携をめざして〜, 2022年09月26日 - 〔主要な業績〕世界に飛び立つためにこんな準備をしました
講師
日本畜産学会若手企画委員会主催(一般財団法人旗影会協賛), 若手研究者交流会 「Re:Virtual サイエンスナイト」, 2021年09月14日 - 味覚の科学
講師
2021年度茨城大学WEBオープンキャンパス模擬授業, 2021年07月17日
メディア報道
- 人間の「おいしい」はニワトリに通じない? 実験で見えた味覚の違い
朝日新聞, 2024年01月, 新聞・雑誌 - 心理学的な学習行動を利用してニワトリの味覚を可視化 制限アミノ酸や糖類に反応 嗜好性に寄与する飼料成分の理解に貢献
プレスリリース, 2023年12月, インターネットメディア